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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Htr6tm1Tct
targeted mutation 1, Laurence H Tercott
MGI:3844587
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Htr6tm1Tct/Htr6tm1Tct involves: 129X1/SvJ * C57BL/6J MGI:3844588


Genotype
MGI:3844588
hm1
Allelic
Composition
Htr6tm1Tct/Htr6tm1Tct
Genetic
Background
involves: 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Htr6tm1Tct mutation (0 available); any Htr6 mutation (26 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• no differences in activity level, anxiety related behaviors, circadian rhythms, acoustic startle response, spatial learning, or responses to amphetamine and physostigmine are seen
• increase in activity in the first 5 min after injection of 2 g/kg ethanol compared to similarly treated controls
• decreased sensitivity to alcohol induced ataxia and sedation
• however, mice do not show altered preference for alcohol compared to controls

growth/size/body
N
• unlike mice homozygous for other null alleles of this gene, body weight is similar to controls





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory