Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il17ftm1Awai mutation
(0 available);
any
Il17f mutation
(27 available)
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immune system
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• there is no difference in onset or severity of experimental autoimmune encephalomyelitis induced by myelin oligodendrocyte glycoprotein peptide (MOG) compared to controls even when IL-17A was neutralized by antibody treatment
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• Th17 polarized splenocytes do not produce IL-17F and produce less IL-17A in vitro
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Allelic
Composition |
Il17ftm1Awai/Il17f+
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Genetic
Background |
involves: 129S6/SvEvTac * C57BL/6 |
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il17ftm1Awai mutation
(0 available);
any
Il17f mutation
(27 available)
|
|
|
immune system
|
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• Th17-polarized splenocytes produce less IL-17F than controls
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Analysis Tools