Mouse Genome Informatics
tg1
    Tg(Thy1-MAPT*V337M)1Godt/0
involves: C57BL/6J * CBA/Ca
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• mice exhibit normal motor functions
• in 5-choice serial reaction time task (5-CSRTT), old mice exhibit increased impulsive behaviors compared to wild-type mice
• in 5-CSRTT tests with task manipulations, young and old mice exhibit increased impulsive behavior compared to wild-type mice
• increased impulsive behaviors are exacerbated by age

Mouse Models of Human Disease
OMIM IDRef(s)
Frontotemporal Dementia; FTD 600274 J:143018