About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dlgap5tm1Tfts
targeted mutation 1, Ting-Fen Tsai
MGI:3821727
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dlgap5tm1Tfts/Dlgap5tm1Tfts involves: 129S7/SvEvBrd MGI:3821728


Genotype
MGI:3821728
hm1
Allelic
Composition		 Dlgap5tm1Tfts/Dlgap5tm1Tfts
Genetic
Background		 involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dlgap5tm1Tfts mutation (2 available); any Dlgap5 mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:142315 )
N
• ovarian function and fertilization are normal
• males are fertile
abnormal decidualization ( J:142315 )
• fail to show any signs of decidualization following artificial induction of the decidual reaction
• endometrial stromal proliferation is severely impaired on days 4 and 5 of pregnancy as the result of a pre-mitotic block leading to impaired cell cycle progression
female infertility ( J:142315 )
• females are infertile due to a defect in implantation

embryo
abnormal decidualization ( J:142315 )
• fail to show any signs of decidualization following artificial induction of the decidual reaction
• endometrial stromal proliferation is severely impaired on days 4 and 5 of pregnancy as the result of a pre-mitotic block leading to impaired cell cycle progression




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory