• mice exhibit retardation of development in a homing test with increased latency to reach the goal arena compared to wild-type mice

• mice spend more time than wild-type mice in the arms of an elevated plus maze and exhibit reduced emotionality

• in a wire suspension test, P14 mice exhibit a reduced latency to fall compared to wild-type mice

• in the coat hanger test, adult mice exhibit a reduced latency to fall compared to wild-type mice and the number of crossing along the bar was reduced compared to in wild-type mice

• in a pivoting test, mice exhibit more turnings at P10 than wild-type mice

• mice exhibit a delay in acquisition and maturation of locomotion from cranial to caudal parts of the body

• at P7, mice exhibit an increased latency to initiate walking compared to wild-type mice

• mice exhibit increased activity in the periphery and center of the arena in an open field test and in an elevated plus maze comapred to wild-type mice

• mice exhibit a delay in maturation of gait and a persistence of immature locomotor patterns