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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Cyp4v3tm1(KOMP)Vlcg
targeted mutation 1, Velocigene
MGI:3808361
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Cyp4v3tm1(KOMP)Vlcg/Cyp4v3tm1(KOMP)Vlcg B6(Cg)-Cyp4v3tm1(KOMP)Vlcg MGI:5804204


Genotype
MGI:5804204
hm1
Allelic
Composition
Cyp4v3tm1(KOMP)Vlcg/Cyp4v3tm1(KOMP)Vlcg
Genetic
Background
B6(Cg)-Cyp4v3tm1(KOMP)Vlcg
Cell Lines 10578B-B5
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cyp4v3tm1(KOMP)Vlcg mutation (0 available); any Cyp4v3 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• plasma levels of C18:0 fatty acids are lower while C18:2 and C18:3 levels are higher in 12 month old mice

vision/eye
• mice exhibit corneoretinal crystal accumulation beginning at 6 months with confluent crystalline deposits by 12 months of age
• 12 month old eyes show focal accumulation of Oil Red O lipid droplets within the choroid layer

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Bietti crystalline corneoretinal dystrophy DOID:0050664 OMIM:210370
J:230232





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/30/2021
MGI 6.16
The Jackson Laboratory