Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bhlhe41tm1Mjro mutation
(1 available);
any
Bhlhe41 mutation
(12 available)
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behavior/neurological
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• following an 8 hours light dark cycle delay (experimental jet lag), mice exhibit a delayed behavioral re-entrainment compared to wild-type mice that is not as severe as in Bhlhb2tm1Tan homozygotes or compound Bhlhb2 and Blbhb3 mice
• however, rhythmicity of wheel running during light dark and dark dark phases is normal
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bhlhe40tm1Tan mutation
(0 available);
any
Bhlhe40 mutation
(50 available)
Bhlhe41tm1Mjro mutation
(1 available);
any
Bhlhe41 mutation
(12 available)
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behavior/neurological
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• free-running period length in constant darkness following light dark entrainment is lengthened compared to in wild-type mice
• however, rhythmicity of wheel running during light dark and dark dark phases is normal
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• phase shift responses are lengthened
• however, the photic phase response curve is normal
• following an 8 hours light dark cycle delay (experimental jet lag), mice exhibit significant delayed behavioral re-entrainment compared to wild-type mice
|
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bhlhe40tm1Tan mutation
(0 available);
any
Bhlhe40 mutation
(50 available)
Bhlhe41tm1Mjro mutation
(1 available);
any
Bhlhe41 mutation
(12 available)
|
|
|
behavior/neurological
|
|
• free-running period length in constant darkness following light dark entrainment is lengthened compared to in wild-type mice
• however, rhythmicity of wheel running during light dark and dark dark phases is normal
|
|
|
• following an 8 hours light dark cycle delay (experimental jet lag), mice exhibit significant delayed behavioral re-entrainment compared to wild-type mice that is not greater than in Bhlhb2tm1Tan homozygotes
|
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bhlhe40tm1Tan mutation
(0 available);
any
Bhlhe40 mutation
(50 available)
Bhlhe41tm1Mjro mutation
(1 available);
any
Bhlhe41 mutation
(12 available)
|
|
|
behavior/neurological
|
|
• free-running period length in constant darkness following light dark entrainment is lengthened compared to in wild-type mice
• however, rhythmicity of wheel running during light dark and dark dark phases is normal
|
|
|
• following an 8 hours light dark cycle delay (experimental jet lag), mice exhibit significant delayed behavioral re-entrainment compared to wild-type mice that is not greater than in Bhlhb2tm1Tan homozygotes
|
Analysis Tools