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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Pax2-cre)1Dje
transgene insertion 1, Douglas J Epstein
MGI:3797084
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Bmp4tm1Blh/Bmp4tm4Blh
Tg(Pax2-cre)1Dje/0 		involves: 129S2/SvPas * 129S6/SvEvTac * Black Swiss * C57BL/6 * SJL MGI:3805991


Genotype
MGI:3805991
cn1
Allelic
Composition		 Bmp4tm1Blh/Bmp4tm4Blh
Tg(Pax2-cre)1Dje/0
Genetic
Background		 involves: 129S2/SvPas * 129S6/SvEvTac * Black Swiss * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmp4tm1Blh mutation (2 available); any Bmp4 mutation (21 available)
Bmp4tm4Blh mutation (0 available); any Bmp4 mutation (21 available)
Tg(Pax2-cre)1Dje mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
abnormal inner ear morphology ( J:136636 )
• tow thirds of embryos have inner ear defects; more mildly affected embryos show defects in the three ampullae and canals
abnormal semicircular canal morphology ( J:136636 )
• canal defects (in addition to lateral canal truncations) are observed in mildly affected embryos
abnormal utricle morphology ( J:136636 )
• malformed in more severely affected embryos
abnormal vestibular saccule morphology ( J:136636 )
• malformed in more severely affected embryos




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory