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Allele Symbol Allele Name Allele ID |
Ddx20tm1Yosa targeted mutation 1, Yoel Sadovsky MGI:3795148 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• embryos fail to implant and do not progress past the 2 cell stage
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• embryos do not progress past the 2 cell stage
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• about 25% of follicles are devoid of oocytes, which is significantly higher than in wild-type females (about 5%)
• empty follicles are found at every stage of maturation
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• ovaries are about 50% heavier than in wild-type controls
• there is no significant differences in weight of testes or adrenal glands
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• females have significantly less serum levels of ACTH in evenings and after 30 minutes of restraint stress compared to female controls
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• about 25% of follicles are devoid of oocytes, which is significantly higher than in wild-type females (about 5%)
• empty follicles are found at every stage of maturation
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• ovaries are about 50% heavier than in wild-type controls
• there is no significant differences in weight of testes or adrenal glands
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• females spend more time in estrous (42%) than do female controls (27%)
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• ovaries are about 50% heavier than in wild-type controls
• there is no significant differences in weight of testes or adrenal glands
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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