Phenotypes associated with this allele

• Allele Symbol: Tor1a^tm2Yql
• Allele Name: targeted mutation 2, Yuqing Li
• Allele ID: MGI:3772564
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Emx1^tm1(cre)Yql/Emx1^+ Tor1a^tm2Yql/Tor1a^tm2Yql	involves: 129S2/SvPas * 129S4/SvJae * C57BL/6	MGI:3772569

Genotype
MGI:3772569

cn1

• Allelic Composition: Emx1^tm1(cre)Yql/Emx1⁺; Tor1a^tm2Yql/Tor1a^tm2Yql
• Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal motor coordination/balance ( J:130483 )

• on a beam-walking test, 71% of mice exhibit more falls than wild-type mice

• however, mice perform normally in a rotarod test

abnormal gait ( J:130483 )

• the hind base of male mice is smaller than in wild-type mice

hyperactivity ( J:130483 )

• mice exhibit hyperactivity in an open-field test

circling ( J:130483 )

increased stereotypic behavior ( J:130483 )

nervous system

nervous system phenotype ( J:130483 )

N • the cerebral cortex and dopamine metabolite levels are normal