All Phenotypes Pou5f1<tm1Jae> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pou5f1^tm1Jae
targeted mutation 1, Rudolf Jaenisch
MGI:3771368

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pou5f1^tm1Jae/Pou5f1^tm1Jae	involves: 129S4/SvJae * C57BL/6	MGI:3772226

Allelic Composition	Pou5f1^tm1Jae/Pou5f1^tm1Jae
Genetic Background	involves: 129S4/SvJae * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pou5f1^tm1Jae mutation (1 available); any Pou5f1 mutation (82 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:130250 )

• mice are viable and fertile; some murine embryonic fibroblasts treated with specific transcription factors (Pou5f1, Sox2, c-myc, and Klf4) have the properties of induced pluripotent stem (iPS) cells. Such iPS cells have the DNA methylation, gene expression and chromatin state of embryonic stem cells and can form viable chimeras, contribute to the germ line, and generate live late-term embryos when injected into tetraploid blastocysts.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23