Phenotypes associated with this allele

• Allele Symbol: Oxt^tm3Ljm
• Allele Name: targeted mutation 3, Louis J Muglia
• Allele ID: MGI:3771291
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Oxt^tm3Ljm/Oxt^tm3Ljm	either: B6.129S2-Oxt^tm3Ljm or B6.129S6-Oxt^tm3Ljm	MGI:3771294

Genotype
MGI:3771294

hm1

• Allelic Composition: Oxt^tm3Ljm/Oxt^tm3Ljm
• Genetic Background: either: B6.129S2-Oxt^tm3Ljm or B6.129S6-Oxt^tm3Ljm

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

pregnancy-related premature death ( J:130046 )

♀ • 2 mice die due to failed labor

reproductive system

abnormal parturition ( J:130046 )

♀ • mice exposed to a shifted light cycle exhibit a random shift in labor with respect to time of day unlike wild-type mice that do not exhibit a shift in the absolute time of labor

♀ • 2 mice die due to failed labor

behavior/neurological

abnormal circadian behavior ( J:130046 )

• mice exposed to a shifted light cycle exhibit a random shift in labor with respect to time of day unlike wild-type mice that do not exhibit a shift in the absolute time of labor

• however, locomotor activity adjusts normally to a shift in the light cycle