All Phenotypes Twist1<tm2.1Bhr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Twist1^tm2.1Bhr
targeted mutation 2.1, Richard R Behringer
MGI:3768519

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Twist1^tm1Bhr/Twist1^tm2.1Bhr	involves: 129S7/SvEvBrd * C57BL/6J	MGI:3768521

Allelic Composition	Twist1^tm1Bhr/Twist1^tm2.1Bhr
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Twist1^tm1Bhr mutation (4 available); any Twist1 mutation (18 available)
Twist1^tm2.1Bhr mutation (0 available); any Twist1 mutation (18 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

internal hemorrhage ( J:128714 )

• at E11.5, blood pooling in the cranial region is observed

limbs/digits/tail

abnormal forelimb morphology ( J:128714 )

• at E11.5, forelimbs are reduced in size compared to wild-type mice

nervous system

exencephaly ( J:128714 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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