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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(tetO-Arntl)1Jt
transgene insertion 1, Joseph S Takahashi
MGI:3714756
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Arntltm1Bra/Arntltm1Bra
Tg(Scg2-tTA)1Jt/0
Tg(tetO-Arntl)1Jt/0
involves: 129/Sv * C57BL/6J * CD-1 MGI:3714773


Genotype
MGI:3714773
cx1
Allelic
Composition
Arntltm1Bra/Arntltm1Bra
Tg(Scg2-tTA)1Jt/0
Tg(tetO-Arntl)1Jt/0
Genetic
Background
involves: 129/Sv * C57BL/6J * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arntltm1Bra mutation (1 available); any Arntl mutation (128 available)
Tg(Scg2-tTA)1Jt mutation (1 available)
Tg(tetO-Arntl)1Jt mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• rescued mice exhibit a consistent circadian rhythm (without doxycycline-treatment) which is abolished within 1 to 2 days of doxycycline treatment, then regained after doxycycline withdrawal
• free-running period of rescued mice (bitransgenic null mice without doxycycline treatment) is about 1 hour shorter than in wild-type
• although circadian rhythm is restored, level activity and amplitude are significantly lower than observed in wild-type





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last database update
01/04/2022
MGI 6.17
The Jackson Laboratory