Mouse Genome Informatics
cx1
     Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-APPSwInd)102Dbo/0
involves: C3H/HeJ * C57BL/6 * CBA
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
nervous system
abnormal nervous system physiology ( J:109829 )
• mice produce transgenic APP protein at 10- to 30-fold over endogenous App levels
• suppression of transgene expression in these mice is most sensitive to doxycycline of the four lines tested

Mouse Models of Human Disease
 OMIM IDRef(s)
Alzheimer Disease; AD 104300 J:109829


Mouse Genome Informatics
tg2
     Tg(tetO-APPSwInd)102Dbo/0
involves: C3H/HeJ * C57BL/6J
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
phenotype not analyzed
no phenotypic analysis ( J:109829 )
• no analysis of single transgenic mice provided

Mouse Models of Human Disease
 OMIM IDRef(s)
Alzheimer Disease; AD 104300 J:109829