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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sox10m2C57BL/6J
C57BL/6J
MGI:3699508
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Sox10m2C57BL/6J/Sox10m2C57BL/6J
Sox10Dom/Sox10Dom 		involves: C3HeB/FeJ * C57BL/6J MGI:3699519
cx2
 		Sox10m2C3HeB/FeJ/Sox10m2C57BL/6J
Sox10Dom/Sox10Dom 		involves: C3HeB/FeJ * C57BL/6J MGI:3699591


Genotype
MGI:3699519
cx1
Allelic
Composition		 Sox10m2C57BL/6J/Sox10m2C57BL/6J
Sox10Dom/Sox10Dom
Genetic
Background		 involves: C3HeB/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox10Dom mutation (1 available); any Sox10 mutation (33 available)
Sox10m2C57BL/6J mutation (0 available); any Sox10m2 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
aganglionic megacolon ( J:118320 )
• increased aganglionosis severity
• increased aganglionosis penetrance
• increased affected gut length




Genotype
MGI:3699591
cx2
Allelic
Composition		 Sox10m2C3HeB/FeJ/Sox10m2C57BL/6J
Sox10Dom/Sox10Dom
Genetic
Background		 involves: C3HeB/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox10Dom mutation (1 available); any Sox10 mutation (33 available)
Sox10m2C3HeB/FeJ mutation (0 available); any Sox10m2 mutation (0 available)
Sox10m2C57BL/6J mutation (0 available); any Sox10m2 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
abnormal intestine morphology ( J:117027 )
• increased gut length
aganglionic megacolon ( J:118320 )
• increased aganglionosis severity
• increased aganglionosis penetrance
• increased affected gut length




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory