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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ptf1atm2.1Mgn
targeted mutation 2.1, Mark A Magnuson
MGI:3691484
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ptf1atm2.1Mgn/Ptf1atm2.1Mgn Not Specified MGI:3695167


Genotype
MGI:3695167
hm1
Allelic
Composition		 Ptf1atm2.1Mgn/Ptf1atm2.1Mgn
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptf1atm2.1Mgn mutation (1 available); any Ptf1a mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
increased retina ganglion cell number ( J:115271 )
• precursors normally fated to become amacrine and horizontal cells switch to ganglion cell fates, resulting in an increase in ganglion cells

nervous system
increased retina ganglion cell number ( J:115271 )
• precursors normally fated to become amacrine and horizontal cells switch to ganglion cell fates, resulting in an increase in ganglion cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory