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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Soaa
sucrose octaacetate aversion, a variant
MGI:3689003
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Soaa/Soaa SWR MGI:3798650
ht2
Soaa/Soac C3FeJ.SW-Soaa/Soac MGI:3798789


Genotype
MGI:3798650
hm1
Allelic
Composition
Soaa/Soaa
Genetic
Background
SWR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Soaa mutation (1 available); any Soa mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
taste/olfaction
• Background Sensitivity: mice have a higher aversion for drinking water containing calcium hydroxide than the C3HeB strain or SWR mice heterozygote for the Soaa allele
• mice demonstrate a strong aversion to the bitter tasting compound sucrose octaacetate (SOA) when present in drinking water at 100 micromolar concentrations compared to thirty other in-bred strains that had no aversion to SOA at this concentration (J:6574)
• mice avoid drinking water containing 0.1 mM of the bitter acetylated sugar sucrose octaacetate (SOA) compared to C3HeB/Fe mice that do not show any aversion to SOA at this concentration (J:44684)
• strong taste aversion to SOA occurs at concentrations as low as 3 micromolar while C3HeB mice only display moderate taste aversion at 1 mM (J:44684)
• mice also have strong taste aversions to drinking water containing 0.01 to 1 mM of brucine, strychnine, 6-n-propyl-2 thiouracil or 0.1mM denatonium benzoate while C3Heb mice do not display taste aversions at these concentrations (J:44684)
• mice exhibit taste aversion to quinine compounds at low concentrations (0.03 mM-0.1 mM) while control C3HeB mice only exhibit taste aversions at higher concentrations (0.3 mM-1 mM) (J:44684)
• Background Sensitivity: aversion to water containing low concentrations of caffeine, cyclohexamide, and thiamine occurs in SWR mice while SWR mice heterozygote for the Soaa allele do not have aversion for these compounds at low concentrations (J:44684)




Genotype
MGI:3798789
ht2
Allelic
Composition
Soaa/Soac
Genetic
Background
C3FeJ.SW-Soaa/Soac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Soaa mutation (1 available); any Soa mutation (2 available)
Soac mutation (0 available); any Soa mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
taste/olfaction
• mice carrying the Soaa allele are phenotyped by their taste aversion to drinking water containing 0.1 mM of the bitter acetylated sugar sucrose octaacetate (SOA)
• strong taste aversion to SOA occurs at concentrations as low as 3 micromolar while C3HeB mice only display moderate taste aversion at 1mM
• mice also have strong taste aversions to drinking water containing 0.01 to 1 mM of brucine, strychnine, 6-n-propyl-2 thiouracil or 0.1 mM denatonium benzoate while C3Heb mice do not display taste aversions at these concentrations
• mice exhibit taste aversion to quinine compounds at low concentrations (0.03 mM-0.1 mM) while control C3HeB mice only exhibit taste aversions at higher concentrations (0.3 mM-1 mM)
• mice do not have taste aversion for low concentrations of caffeine, cyclohexamide, and thiamine unlike the background SWR strain that does exhibit taste aversions





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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory