Phenotypes associated with this allele

• Allele Symbol: Hnf4g^tm1Dgen
• Allele Name: targeted mutation 1, Deltagen
• Allele ID: MGI:3664775
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hnf4g^tm1Dgen/Hnf4g^tm1Dgen	involves: 129P2/OlaHsd * C57BL/6	MGI:3665442

Genotype
MGI:3665442

hm1

• Allelic Composition: Hnf4g^tm1Dgen/Hnf4g^tm1Dgen
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

increased body weight ( J:113034 )

• at 7 weeks of age body weight in higher in homozygotes vs wild-type by 10%

behavior/neurological

decreased fluid intake ( J:113034 )

• water consumption is significantly lower than in wild-type

decreased food intake ( J:113034 )

• food intake is significantly lower than wild-type

decreased coping response ( J:113034 )

• mice display significantly more time in a passive state (187%) in the forced swim test than wild-type

abnormal locomotor activation ( J:113034 )

• mice show reduced locomotor activity at night vs wild-type

abnormal nest building behavior ( J:113034 )

• mice are less inclined to build nests

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:113034 )

N • no significant differences in body temperature, body composition or bone parameters are observed compared to wild-type

abnormal energy expenditure ( J:113034 )

• mutants have lower energy expenditure at night

respiratory system

abnormal respiration ( J:113034 )

• mice have lower respiratory exchange ratio which correlates to energy expenditure

• resting lung parameters are not different from wild-type