All Phenotypes Srd5a3<Gt(OST436695)Lex> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Srd5a3^{Gt(OST436695)Lex}
gene trap OST436695, Lexicon Genetics
MGI:3604528

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Srd5a3^{Gt(OST436695)Lex}/Srd5a3^{Gt(OST436695)Lex}	involves: 129S5/SvEvBrd * C57BL/6J	MGI:3609907

Allelic Composition	Srd5a3^{Gt(OST436695)Lex}/Srd5a3^{Gt(OST436695)Lex}
Genetic Background	involves: 129S5/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srd5a3^{Gt(OST436695)Lex} mutation (2 available); any Srd5a3 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:163281 )

• mice die between E11.5 and E13.5

preweaning lethality, complete penetrance ( J:103485 )

• no homozygotes seen at weaning; stage of lethality not specified

embryo

failure of initiation of embryo turning ( J:163281 )

• at E10.5, mice fail to rotate unlike wild-type mice

open neural tube ( J:163281 )

cardiovascular system

dilated heart ( J:163281 )

• at E10.5

nervous system

open neural tube ( J:163281 )

growth/size/body

abnormal ventral body wall morphology ( J:163281 )

• at E10.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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