Phenotypes associated with this allele

• Allele Symbol: Rho^tm2Jlem
• Allele Name: targeted mutation 2, Janis Lem
• Allele ID: MGI:3590580
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rho^tm2Jlem/Rho^tm2Jlem	involves: 129S4/SvJae * C57BL/6	MGI:3617369

Genotype
MGI:3617369

hm1

• Allelic Composition: Rho^tm2Jlem/Rho^tm2Jlem
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

decreased retina rod cell number ( J:100845 )

• the decrease in nuclei in the outer nuclear layer indicate a loss of about 10% of rods

short retina rod cell outer segment ( J:100845 )

• at 12 months of age rod outer segment lengths are slightly shortened

thin retina outer nuclear layer ( J:100845 )

• at 12 months of age the outer nuclear layer is decreased by nearly 1 row of nuclei

retina degeneration ( J:100845 )

• mild retinal degeneration is seen at 12 months of age

nervous system

decreased retina rod cell number ( J:100845 )

• the decrease in nuclei in the outer nuclear layer indicate a loss of about 10% of rods

short retina rod cell outer segment ( J:100845 )

• at 12 months of age rod outer segment lengths are slightly shortened