growth/size
|
• smaller at birth and stay small throughout life, however levels of testosterone, estrogen, thyroid stimulating hormone, and thyroxin are normal
|
|
• more pronounced in males than females, although seen in both
|
reproductive system
|
• average litter size is 4.4 pups compared to 8.4 pups in wild-type
|
hematopoietic system
|
• increase in number of megakaryocytes in the spleen
|
skeleton
short tibia
(
J:100826
)
|
• narrower growth plate
|
limbs/digits/tail
short tibia
(
J:100826
)
Mouse Models of Human Disease |
OMIM ID | Ref(s) | |
| Achondroplasia; ACH | 100800 | J:100826 | |