Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pthlhtm1Hmk mutation
(0 available);
any
Pthlh mutation
(19 available)
Tg(Col2a1-GAL4)1Amc mutation
(0 available)
Tg(UAS-IHH)1Amc mutation
(0 available)
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skeleton
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• growth plate is shorted by about 8%
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pthlhtm1Hmk mutation
(0 available);
any
Pthlh mutation
(19 available)
Tg(Col2a1-GAL4)1Amc mutation
(0 available)
Tg(Col2a1-PTHR1*H223R)AHju mutation
(0 available)
Tg(UAS-IHH)1Amc mutation
(0 available)
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skeleton
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• increase in length of the columnar region compared to Pthlh mutant mice that express the constitutively active PTHR1 but do not overexpress IHH
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
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skeleton
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• longitudinal expansion of the growth plate of E17.5 distal tibia
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• increased proliferation of periarticular chondrocytes despite a decrease in the number of periarticular chondrocytes, indicating acceleration of periarticular chondrocyte differentiation
• increase in the number of columnar chondrocytes, however no difference in the proliferation rate of columnar chondrocytes
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• decrease in the number of periarticular chondrocytes
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craniofacial
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• exhibit facial malformations
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growth/size/body
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• exhibit facial malformations
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
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skeleton
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• 20% increase in chondrocyte proliferation at E14.5 and 60% increase at E16.5 in the proliferative zone of the tibia, mainly in the region close to the articular surface of the cartilage
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Analysis Tools
