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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Npr2cn-3J
achondroplasia 3 Jackson
MGI:3583746
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Npr2cn-3J/Npr2cn-3J MRL/MpJ-Npr2cn-3J/GrsrJ MGI:4947978


Genotype
MGI:4947978
hm1
Allelic
Composition
Npr2cn-3J/Npr2cn-3J
Genetic
Background
MRL/MpJ-Npr2cn-3J/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Npr2cn-3J mutation (1 available); any Npr2 mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Disproportionate dwarf phenotype in Npr2cn-3J/Npr2cn-3J mice

growth/size/body
• homozygotes have a shorter body length, short noses, short limbs, short tails, and squared bellies

limbs/digits/tail

craniofacial

reproductive system
• female homozygotes breed poorly and have small litter sizes
• male homozygotes are not able to breed, but this is not due to a sperm defect since sperm functions satisfactorily for in vitro fertilization

Mouse Models of Human Disease
OMIM ID Ref(s)
Achondroplasia; ACH 100800 J:170669





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory