Phenotypes associated with this allele

• Allele Symbol: Il16^tm1Korn
• Allele Name: targeted mutation 1, Hardy Kornfeld
• Allele ID: MGI:3576925
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Il16^tm1Korn/Il16^tm1Korn	either: B6.129X1-Il16^tm1Korn or C.129X1-Il16^tm1Korn	MGI:3578784

Genotype
MGI:3578784

hm1

• Allelic Composition: Il16^tm1Korn/Il16^tm1Korn
• Genetic Background: either: B6.129X1-Il16^tm1Korn or C.129X1-Il16^tm1Korn

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal T cell physiology ( J:97739 )

• following primary stimulation with anti-CD3 mAb in vitro, T cells show a transient, but consistent increase in thymidine incorporation at 72 hours, however there is no net increase in proliferating cells or any difference in the survival of activated T cells and did not show any cell cycle differences in splenic or lymph node CD4+ T cells

hematopoietic system

abnormal T cell physiology ( J:97739 )

• following primary stimulation with anti-CD3 mAb in vitro, T cells show a transient, but consistent increase in thymidine incorporation at 72 hours, however there is no net increase in proliferating cells or any difference in the survival of activated T cells and did not show any cell cycle differences in splenic or lymph node CD4+ T cells