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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		hlb385
heart, lung and blood 385
MGI:3575131
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ot1
 		hlb385/? C57BL/6J-hlb385/J MGI:3575132


Genotype
MGI:3575132
ot1
Allelic
Composition		 hlb385/?
Genetic
Background		 C57BL/6J-hlb385/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
hlb385 mutation (1 available); any hlb385 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased leukocyte cell number ( J:82961 )
• 3.2 x 103 WBC per microliter at 7 weeks of age, a decrease of approximately 60% relative to the wild-type C57BL/6J value of 8.01 +/- 1.28 x 103
• retesting 2 weeks later confirmed leukopenia

hematopoietic system
decreased leukocyte cell number ( J:82961 )
• 3.2 x 103 WBC per microliter at 7 weeks of age, a decrease of approximately 60% relative to the wild-type C57BL/6J value of 8.01 +/- 1.28 x 103
• retesting 2 weeks later confirmed leukopenia




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory