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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Abca7tm1Frm
targeted mutation 1, Mason W Freeman
MGI:3574592
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Abca7tm1Frm/Abca7tm1Frm involves: 129S4/SvJae * C57BL/6 MGI:3574816


Genotype
MGI:3574816
hm1
Allelic
Composition
Abca7tm1Frm/Abca7tm1Frm
Genetic
Background
involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abca7tm1Frm mutation (0 available); any Abca7 mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
adipose tissue
• females, but not males, exhibited an approximate 50% reduction in the white adipose tissue mass at 10 weeks of age

homeostasis/metabolism
• total cholesterol was significantly lower in females but not males, however no alterations in serum-free fatty acid levels
• females exhibited a decrease in HDL cholesterol levels

renal/urinary system
• males exhibit a 10% reduction in kidney size at 10 weeks of age





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/28/2017
MGI 6.11
The Jackson Laboratory