About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
IdeGt(OST132429)Lex
gene trap OST132429, Lexicon Genetics
MGI:3530576
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
IdeGt(OST132429)Lex/IdeGt(OST132429)Lex involves: 129S5/SvEvBrd * C57BL/6-Tyrc MGI:2655698


Genotype
MGI:2655698
hm1
Allelic
Composition
IdeGt(OST132429)Lex/IdeGt(OST132429)Lex
Genetic
Background
involves: 129S5/SvEvBrd * C57BL/6-Tyrc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
IdeGt(OST132429)Lex mutation (2 available); any Ide mutation (68 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• accumulation of amyloid beta in the brain
• hyperglycemia 60 minutes after glucose injection
• insulin levels increased by 2.8-fold
• increased circulating insulin level

nervous system
• accumulation of amyloid beta in the brain





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/09/2024
MGI 6.23
The Jackson Laboratory