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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rtn4rl1Gt(OST188035)Lex
gene trap OST188035, Lexicon Genetics
MGI:3530246
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rtn4rl1Gt(OST188035)Lex/Rtn4rl1Gt(OST188035)Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:3609640


Genotype
MGI:3609640
hm1
Allelic
Composition		 Rtn4rl1Gt(OST188035)Lex/Rtn4rl1Gt(OST188035)Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rtn4rl1Gt(OST188035)Lex mutation (2 available); any Rtn4rl1 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
liver/biliary system
abnormal bile duct morphology ( J:103485 )
• a bile duct lesion is noted in the female mutant
abnormal hepatocyte morphology ( J:103485 )
• enlarged cytoplasmic vacuoles and nuclei are noted in the centrilobular hepatocytes of the male mutant
hepatic steatosis ( J:103485 )
• fatty change in the liver in both the male and female homozygotes

endocrine/exocrine glands
abnormal bile duct morphology ( J:103485 )
• a bile duct lesion is noted in the female mutant




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory