About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cdc25aGt(OST186277)Lex
gene trap OST186277, Lexicon Genetics
MGI:3530222
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cdc25aGt(OST186277)Lex/Cdc25aGt(OST186277)Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:3609658
ht2
 		Cdc25aGt(OST186277)Lex/Cdc25a+ involves: 129S5/SvEvBrd * C57BL/6J MGI:3609659


Genotype
MGI:3609658
hm1
Allelic
Composition		 Cdc25aGt(OST186277)Lex/Cdc25aGt(OST186277)Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdc25aGt(OST186277)Lex mutation (2 available); any Cdc25a mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, complete penetrance ( J:103485 )
• timing of lethality not actually specified




Genotype
MGI:3609659
ht2
Allelic
Composition		 Cdc25aGt(OST186277)Lex/Cdc25a+
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdc25aGt(OST186277)Lex mutation (2 available); any Cdc25a mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
abnormal trabecular bone morphology ( J:103485 )
• male heterozygotes exhibited decreased vertebral trabecular bone volume, number, and thickness




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory