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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Arpp21tm1Lex
targeted mutation 1, Lexicon Genetics
MGI:3529328
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Arpp21tm1Lex/Arpp21tm1Lex involves: 129S5/SvEvBrd * C57BL/6 MGI:3624512


Genotype
MGI:3624512
hm1
Allelic
Composition		 Arpp21tm1Lex/Arpp21tm1Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arpp21tm1Lex mutation (0 available); any Arpp21 mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal channel response ( J:94124 )
• two fold enhancement in the ability of both M1 and D2 receptors to modulate L-type calcium channel currents




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory