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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Cds2Gt(OST184358)Lex
gene trap OST184358, Lexicon Genetics
MGI:3529169
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Cds2Gt(OST184358)Lex/Cds2Gt(OST184358)Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:3609645
ht2
Cds2Gt(OST184358)Lex/Cds2+ involves: 129S5/SvEvBrd * C57BL/6J MGI:3609646


Genotype
MGI:3609645
hm1
Allelic
Composition
Cds2Gt(OST184358)Lex/Cds2Gt(OST184358)Lex
Genetic
Background
involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cds2Gt(OST184358)Lex mutation (2 available); any Cds2 mutation (50 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• timing of lethality not actually specified




Genotype
MGI:3609646
ht2
Allelic
Composition
Cds2Gt(OST184358)Lex/Cds2+
Genetic
Background
involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cds2Gt(OST184358)Lex mutation (2 available); any Cds2 mutation (50 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• decreased mean percentage of B cells
• increased mean percentages of CD4 and CD8 cells

nervous system
• enhanced sensorimotor gating/attention

hematopoietic system
• decreased mean percentage of B cells
• increased mean percentages of CD4 and CD8 cells





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory