All Phenotypes Pzp<tm1Lex> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pzp^tm1Lex
targeted mutation 1, Lexicon Genetics
MGI:3529167

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pzp^tm1Lex/Pzp^tm1Lex	involves: 129S5/SvEvBrd * C57BL/6J	MGI:3609833

Allelic Composition	Pzp^tm1Lex/Pzp^tm1Lex
Genetic Background	involves: 129S5/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pzp^tm1Lex mutation (2 available); any Pzp mutation (79 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

increased bone mineral density ( J:103485 )

• bone mineral density is increased

behavior/neurological

decreased locomotor activity ( J:103485 )

• in homozygous females activity is decreased during a 10 hour habituation period and in the home cage during the dark phase

cardiovascular system

decreased heart rate ( J:103485 )

• decreased mean heart rates are seen in homozygous males

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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