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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Nes-cre)2472Pick
transgene insertion 2472, David J Picketts
MGI:3528493
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Atrxtm1Rjg/Y
Tg(Nes-cre)2472Pick/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N MGI:3530076


Genotype
MGI:3530076
cn1
Allelic
Composition
Atrxtm1Rjg/Y
Tg(Nes-cre)2472Pick/0
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atrxtm1Rjg mutation (0 available); any Atrx mutation (75 available)
Tg(Nes-cre)2472Pick mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• reduced postnatal survival similar to Atrx hemizygotes that are heterozygous for Foxg1tm1(cre)Skm

growth/size/body
• mutants are smaller at birth

nervous system
• not as severe as in Atrx hemizygotes that are heterozygous for Foxg1tm1(cre)Skm
• the frontal cortex is reduced in size especially in the caudal-medial cortex similar to Atrx hemizygotes that are heterozygous for Foxg1tm1(cre)Skm but the severity of loss is decreased





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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory