Phenotypes associated with this allele

• Allele Symbol: Lrrk2^tm1Tmd
• Allele Name: targeted mutation 1, Ted Dawson
• Allele ID: MGI:3514169
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lrrk2^tm1Tmd/Lrrk2^tm1Tmd	involves: 129S/SvEv * C57BL/6	MGI:3834936

Genotype
MGI:3834936

hm1

• Allelic Composition: Lrrk2^tm1Tmd/Lrrk2^tm1Tmd
• Genetic Background: involves: 129S/SvEv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:157100 )

• fewer than expected mice are viable (no time of death given)

behavior/neurological

increased grooming behavior ( J:157100 )

• excessive resulting in alopecia of the muzzle and head

integument

alopecia ( J:157100 )

• centered on the muzzle and head due to excessive grooming