About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ap3b2tm1Bur
targeted mutation 1, Margit Burmeister
MGI:3513518
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ap3b2tm1Bur/Ap3b2tm1Bur C57BL/6-Ap3b2tm1Bur MGI:3522639


Genotype
MGI:3522639
hm1
Allelic
Composition
Ap3b2tm1Bur/Ap3b2tm1Bur
Genetic
Background
C57BL/6-Ap3b2tm1Bur
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ap3b2tm1Bur mutation (1 available); any Ap3b2 mutation (49 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mutants are about twice as active during the first 30 minutes in an open field test
• tonic-clonic seizures

nervous system
• synaptic zinc levels are reduced throughout the brain by on average about 25%, with the largest reduction (about 62% of control) in the CA1 stratum oriens
• tonic-clonic seizures

integument
N
• coat and skin color are normal





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/04/2022
MGI 6.17
The Jackson Laboratory