About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Aqp2tm1.1Ask
targeted mutation 1.1, A S Verkman
MGI:3511258
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Aqp2tm1.1Ask/Aqp2tm1.1Ask involves: C57BL/6J * FVB/N MGI:3511455


Genotype
MGI:3511455
hm1
Allelic
Composition
Aqp2tm1.1Ask/Aqp2tm1.1Ask
Genetic
Background
involves: C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aqp2tm1.1Ask mutation (0 available); any Aqp2 mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mice survive only 8 days after birth

homeostasis/metabolism
• approximately 200 mOsm as opposed to 400 mOsm in controls

renal/urinary system
• approximately 200 mOsm as opposed to 400 mOsm in controls
• showed signs of obstructive uropathy
• some instances in which the medulla was replaced by a large fluid filled cavity
• papillary atrophy





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory