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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(CMV-EGFP,Rnu6-siAbca1)#Wcyy
transgene insertion, Winston C Y Yu
MGI:3510918
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Tg(ALB-cre,CMV-rtTA)#Wcyy/0
Tg(CMV-EGFP,Rnu6-siAbca1)#Wcyy/0
involves: ICR MGI:3510920


Genotype
MGI:3510920
cn1
Allelic
Composition
Tg(ALB-cre,CMV-rtTA)#Wcyy/0
Tg(CMV-EGFP,Rnu6-siAbca1)#Wcyy/0
Genetic
Background
involves: ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• serum cholesterol is reduced 35-40% 5 days after doxycycline treatment compared to untreated controls

liver/biliary system
• lipid accumulation is seen only in the liver after doxycycline treatment

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Tangier disease DOID:1388 OMIM:205400
J:93624





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory