Mouse Genome Informatics

hm1

Enam^Rgsc521/Enam^Rgsc521
involves: C57BL/6JJcl * DBA/2J

Key:
♀	phenotype observed in females	WTSI	Wellcome Trust Sanger Institute
♂	phenotype observed in males	Euro	Europhenome
N	normal phenotype

craniofacial

absent enamel ( J:96349 )

• enamel is absent from the incisors and molars

Mouse Models of Human Disease		OMIM ID	Ref(s)
Amelogenesis Imperfecta, Type IB; AI1B		104500	J:96349

Mouse Genome Informatics

ht2

Enam^Rgsc521/Enam⁺
involves: C57BL/6JJcl * DBA/2J

Key:
♀	phenotype observed in females	WTSI	Wellcome Trust Sanger Institute
♂	phenotype observed in males	Euro	Europhenome
N	normal phenotype

craniofacial

abnormal tooth morphology ( J:96349 )

• a gap is seen between the enamel and the dentin core

abnormal incisor morphology ( J:96349 )

• the incisor occlusion surface shows abnormal wear

abnormal enamel morphology ( J:96349 )

• the enamel surface appears slightly rougher and abnormal wear at the incisor occlusion surface suggests the enamel is softer, but enamel thickness is normal

Mouse Models of Human Disease		OMIM ID	Ref(s)
Amelogenesis Imperfecta, Type IB; AI1B		104500	J:96349