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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(PRG1)18Wlad
transgene insertion 18, Wyeth Lederle/Anne Deatly
MGI:3055287
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(PRG1)18Wlad/0 involves: C57BL/6J * CBA/J MGI:3835114


Genotype
MGI:3835114
tg1
Allelic
Composition
Tg(PRG1)18Wlad/0
Genetic
Background
involves: C57BL/6J * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(PRG1)18Wlad mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• when infected with wild-type III poliovirus mice exhibit lethality unlike wild-type mice

immune system
• onset of disease following exposure to poliovirus is later than in mice expressing Tg(PRG3)9Wlad
• when infected with wild-type III poliovirus mice exhibit paralysis and neuron degeneration unlike wild-type mice
• when infected with wild-type III poliovirus mice exhibit lethality unlike wild-type mice





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory