Phenotypes associated with this allele

• Allele Symbol: tmgc38
• Allele Name: Tennessee Mouse Genome Consortium 38
• Allele ID: MGI:3053563
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	tmgc38/tmgc38	involves: D7R75M	MGI:3514290

Genotype
MGI:3514290

hm1

• Allelic Composition: tmgc38/tmgc38
• Genetic Background: involves: D7R75M

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal mechanical nociception ( J:92490 )

• longer latencies on tail flick and tail clip/pinch tests

hypoalgesia ( J:92490 )

• hypoalgesia to thermal and mechanical pain stimuli

• decreased responsiveness on several assays of pain sensitivity

increased thermal nociceptive threshold ( J:92490 , J:125716 )

• longer latencies at low hotplate temperatures (J:92490)

hearing/vestibular/ear

increased or absent threshold for auditory brainstem response ( J:92490 )

• ABR thresholds are elevated by greater than 20db at 16 kHz (3.7 x SD), but insignificant at click (0.9 x SD), 8 kHz (1.5 x SD), and 32 kHz (1.4 x SD)

impaired hearing ( J:92490 )

• high frequency hearing loss with wide-range component