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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Aadattm1Tag
targeted mutation 1, Danilo A Tagle
MGI:3052711
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Aadattm1Tag/Aadattm1Tag either: (involves: 129S/SvEv) or (involves: 129S/SvEv * Black Swiss) MGI:3053435


Genotype
MGI:3053435
hm1
Allelic
Composition
Aadattm1Tag/Aadattm1Tag
Genetic
Background
either: (involves: 129S/SvEv) or (involves: 129S/SvEv * Black Swiss)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aadattm1Tag mutation (0 available); any Aadat mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mutant pups develop the ability to land in a prone position when dropped sooner than wild-type pups
• at P21 mutant pups display a transient impairment in balance compared to wild-type mice that is not seen at 2 or 6 months of age
• mutant pups display a transient increase in activity in the open field from P17 to P26
• mutant pups acquire the ability to cross an open field earlier than wild-type pups

vision/eye
• mutant eyes open about 1 day earlier compared to wild-type mice

nervous system
• mutant cortical and striatal neurons display a transient increase in spine densities at P21 but not at 2 months of age





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory