Phenotypes associated with this allele

• Allele Symbol: Rasd2^tm1Rdl
• Allele Name: targeted mutation 1, Roberto Di Lauro
• Allele ID: MGI:3050759
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rasd2^tm1Rdl/Rasd2^tm1Rdl	involves: 129S1/Sv * 129X1/SvJ * CD-1	MGI:3050812

Genotype
MGI:3050812

hm1

• Allelic Composition: Rasd2^tm1Rdl/Rasd2^tm1Rdl
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased anxiety-related response ( J:91597 )

• anxiety is increased, particularly in females

• females displayed more anxiety than males, reverse of wild-type

abnormal motor capabilities/coordination/movement ( J:91597 )

impaired coordination ( J:91597 )

• greater tendancy to fall during rota-rod tests than wild-type mic

decreased locomotor activity ( J:91597 )

• moved less in the first 5 minutes of an open field locomotor test

growth/size/body

decreased body weight ( J:91597 )

• lower body weight at all ages tested