Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcc6tm1Jfk mutation
(1 available);
any
Abcc6 mutation
(74 available)
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integument
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• calcification of the fibrous capsule surrounding the muzzle vibrissae occurs at 15 weeks of age
• calcification is less severe than when combined with the Enpp1asj allele
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growth/size/body
homeostasis/metabolism
craniofacial
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcc6tm1Jfk mutation
(1 available);
any
Abcc6 mutation
(74 available)
|
|
|
vision/eye
cardiovascular system
renal/urinary system
integument
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• the capsule surrounding the vibrissae shows progressive mineralization of collagen fibrils and elastic fibers starting around 5 weeks of age
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homeostasis/metabolism
homeostasis/metabolism
integument
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• muzzle skin following initiation of a diet that accelerates ectopic mineralization shows progressive mineralization of connective tissue sheath of vibrissae and calcium deposits; mineralization levels are similar to that seen in single Abcc5tm1Jfk homozygotes
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homeostasis/metabolism
integument
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• calcification of the fibrous capsule surrounding the muzzle vibrissae occurs at 15 weeks of age
• calcification is more severe than with the Abcc6tm1Jfk null allele alone and slightly less severe than in double null mutant
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growth/size/body
craniofacial
integument
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• severe calcification of the fibrous capsule surrounding the muzzle vibrissae by 15 weeks of age
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growth/size/body
homeostasis/metabolism
craniofacial
homeostasis/metabolism
integument
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• mild calcification of the fibrous capsule surrounding the muzzle vibrissae is observed by one year of age
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growth/size/body
craniofacial