• 1 in 7 homozygous mice die after 9 days on a phytol supplemented diet

• after 6 weeks on a phytol supplemented diet the fatpads in homozygous mice are 62% smaller than in homozygous mice on a normal chow diet

• after 6 weeks on a phytol supplemented diet homozygous mice weigh 10% less than wild-type mice while no weight difference is detected on a normal chow diet

• cholesterol concentrations are about 50% lower on either a normal chow diet or a phytol supplemented diet in homozygous mice compared to wild-type mice

• after 6 weeks on a phytol supplemented diet serum alkaline phosphatase levels areincreased 175% in homozygous mice compared to wild-type mice

• after 6 weeks on a phytol supplemented diet homozygous mice had decreased palmitic, oleic, and stearic acid concentrations

• after 6 weeks on a phytol supplemented diet homozygous mice had increased phytanic and pristanic acid concentrations

• after 6 weeks on a phytol supplemented diet triacylglycerols are reduced 52% in homozygous mice compared to wild-type mice

• after 6 weeks on a phytol supplemented diet liver size increases to a great extent in homozygous mice compared to wild-type mice

• after 6 weeks on a phytol supplemented diet livers of homozygous mice display accumulation of lymphocytes and Kupffer's cells, multivacuolar degeneration, and coagulation necrosis

• proliferation of enlarged and unevenly shaped smooth endoplasmic reticulum and peroxisomes is also seen

• the concentration of C24 bile acid species is reduced and the concentration of C27 bile acid precursors is increased 100 - 200 times