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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ercc5tm4Shm
targeted mutation 4, Tadahiro Shiomi
MGI:3043590
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ercc5tm4Shm/Ercc5tm4Shm involves: 129S1/Sv * 129X1/SvJ * C57BL/6J MGI:3043695


Genotype
MGI:3043695
hm1
Allelic
Composition
Ercc5tm4Shm/Ercc5tm4Shm
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ercc5tm4Shm mutation (0 available); any Ercc5 mutation (28 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• homozygous mice have a normal lifespan

growth/size/body
N
• homozygous mice do not display any growth abnormalities

homeostasis/metabolism
• cells from homozygous mutants are more sensitive to UV light than cells from wild-type mice but not as sensitive as cells from Ercc5tm1Shm
• UV induced DNA lesions are partially removed in homozygous mutant cel

integument
• cells from homozygous mutants are more sensitive to UV light than cells from wild-type mice but not as sensitive as cells from Ercc5tm1Shm
• UV induced DNA lesions are partially removed in homozygous mutant cel

Mouse Models of Human Disease
OMIM ID Ref(s)
Xeroderma Pigmentosum, Complementation Group G; XPG 278780 J:89911





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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory