Mouse Genome Informatics
hm1
    Ercc5tm4Shm/Ercc5tm4Shm
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
mortality/aging
N
• homozygous mice have a normal lifespan (J:89911)

growth/size/body
N
• homozygous mice do not display any growth abnormalities (J:89911)

homeostasis/metabolism
• cells from homozygous mutants are more sensitive to UV light than cells from wild-type mice but not as sensitive as cells from Ercc5tm1Shm
• UV induced DNA lesions are partially removed in homozygous mutant cel

integument
• cells from homozygous mutants are more sensitive to UV light than cells from wild-type mice but not as sensitive as cells from Ercc5tm1Shm
• UV induced DNA lesions are partially removed in homozygous mutant cel

Mouse Models of Human Disease
OMIM IDRef(s)
Xeroderma Pigmentosum, Complementation Group G; XPG 278780 J:89911