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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(WapTAg)1Knw
transgene insertion 1, Barbara B Knowles
MGI:3040314
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(WapTAg)1Knw/0 C57BL/6J-Tg(WapTAg)1Knw/J MGI:3581641


Genotype
MGI:3581641
tg1
Allelic
Composition
Tg(WapTAg)1Knw/0
Genetic
Background
C57BL/6J-Tg(WapTAg)1Knw/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(WapTAg)1Knw mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• mammary adenocarcinoma is found in multiparous females but not males or virgin females, with an average latency of 13 months
• in males and virgin females, but not multiparous females, poorly differentiated soft cell sarcomas are observed frequently, usually on the trunk or extremities, with average latency of 13 months

endocrine/exocrine glands
• mammary adenocarcinoma is found in multiparous females but not males or virgin females, with an average latency of 13 months

integument
• mammary adenocarcinoma is found in multiparous females but not males or virgin females, with an average latency of 13 months

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
breast cancer DOID:1612 OMIM:114480
J:53175





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory