All Phenotypes Idd10<NOD/ShiLt> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Idd10^NOD/ShiLt
NOD/ShiLt
MGI:3036798

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Idd10^NOD/ShiLt/Idd10^NOD/ShiLt Idd3^NOD/Idd3^NOD	B6.NOD-Idd3^NOD Idd10^NOD/Lt	MGI:3044052

Allelic Composition	Idd10^NOD/ShiLt/Idd10^NOD/ShiLt Idd3^NOD/Idd3^NOD
Genetic Background	B6.NOD-Idd3^NOD Idd10^NOD/Lt

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Idd10^NOD/ShiLt mutation (2 available); any Idd10 mutation (10 available)
Idd3^NOD mutation (2 available); any Idd3 mutation (12 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal NK T cell physiology ( J:85823 )

• decreased cytokine response of iNKT cells when stimulated with antigens

abnormal cytokine secretion ( J:85823 )

• decreased cytokine response (IL-2, IL-4, IFN-gamma, CSF-1) of iNKT cells when stimulated with antigens

hematopoietic system

abnormal NK T cell physiology ( J:85823 )

• decreased cytokine response of iNKT cells when stimulated with antigens

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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