Phenotypes associated with this allele

• Allele Symbol: Cd44^tm1Ugu
• Allele Name: targeted mutation 1, Ursula Gunthert
• Allele ID: MGI:2679704
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cd44^tm1Ugu/Cd44^tm1Ugu	involves: 129/Sv * C57BL/6	MGI:2679728

Genotype
MGI:2679728

hm1

• Allelic Composition: Cd44^tm1Ugu/Cd44^tm1Ugu
• Genetic Background: involves: 129/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

digestive/alimentary system

abnormal digestive system physiology ( J:62867 )

• 3-4X increase of apoptotic cells in colons after injury but not without injury

immune system

immune system phenotype ( J:62867 )

N • 81% as opposed to 44% of mice survived acute colon injury and did not develop colitis

abnormal T-helper 1 physiology ( J:62867 )

• Th1-type cytokines down regulated

abnormal T-helper 2 physiology ( J:62867 )

• Th2-type cytokines up regulated

hematopoietic system

abnormal T-helper 1 physiology ( J:62867 )

• Th1-type cytokines down regulated

abnormal T-helper 2 physiology ( J:62867 )

• Th2-type cytokines up regulated