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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
l11Jus16
lethal, Chr 11, Justice 16
MGI:2671887
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
l11Jus16/l11Jus16 involves: C57BL/6J MGI:2673662
hm2
l11Jus16/l11Jus16 involves: C57BL/6J * FVB/N MGI:4822146


Genotype
MGI:2673662
hm1
Allelic
Composition
l11Jus16/l11Jus16
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• animals die after birth; 19% die between birth and weaning (J:109155)
• animals die after birth; 19% die between birth and weaning (J:109155)




Genotype
MGI:4822146
hm2
Allelic
Composition
l11Jus16/l11Jus16
Genetic
Background
involves: C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
• mice exhibit L-loop ventricles and situs inversus in the heart (J:163196)
• mice exhibit L-loop ventricles and situs inversus in the heart (J:163196)
• in 3 of 17 mice (J:163196)
• in 3 of 17 mice (J:163196)
• observed in 2 of 17 mutant mice (J:163196)
• observed in 2 of 17 mutant mice (J:163196)
• AVSD with dextrocardia is seen in 2 of 17 mice (J:163196)
• AVSD with levocardia is seen in 3 of 17 mice (J:163196)
• AVSD with dextrocardia is seen in 2 of 17 mice (J:163196)
• AVSD with levocardia is seen in 3 of 17 mice (J:163196)
• mutant mice develop atrioventricular septal defects with complete penetrance and variable expressivity (J:163196)
• mutant mice develop atrioventricular septal defects with complete penetrance and variable expressivity (J:163196)
• 1 in 17 mice exhibit muscular ventricular septal defect (J:163196)
• 1 in 17 mice exhibit muscular ventricular septal defect (J:163196)

growth/size/body
• mutant mice exhibit situs inversus in the heart (J:163196)
• mutant mice exhibit situs inversus in the heart (J:163196)

Mouse Models of Human Disease
OMIM ID Ref(s)
Atrioventricular Septal Defect; AVSD 606215 J:163196





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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory